How many carbs are in a Domino's Pepperoni Pizza Slice (large)?
A 1 slice (110g) serving of Domino's Pepperoni Pizza Slice (large) contains 36g of total carbs (34g net carbs), 3g sugar, 320 calories, 13g protein, 14g fat and 2g fiber.
- Calories
- 320 cal
- Carbohydrates
- 36 g
- of which Sugars
- 3 g
- Fiber
- 2 g
- Net carbs
- 34 g
- Protein
- 13 g
- Fat
- 14 g
Domino's Pepperoni Pizza Slice (large) nutrition at a glance
Per 1 slice (110g), Domino's Pepperoni Pizza Slice (large) delivers about 16% of a 2,000-calorie daily reference, 13% of the 275g daily carbohydrate reference and 7% of the 28g daily fiber reference. Sugar sits at 6% of the 50g added-sugar reference and protein contributes 26% of the 50g protein reference.
- Calories
- 291
- Carbs
- 32.7 g
- Sugar
- 2.7 g
- Protein
- 11.8 g
- Fat
- 12.7 g
- Fiber
- 1.8 g
Blood-sugar impact of Domino's Pepperoni Pizza Slice (large)
Moderate glycemic impact expected. If you're monitoring blood sugar, keep an eye on total portion size and combine with protein or fat.
With 36g total carbs and 2g fiber, the net-carb figure for a 1 slice (110g) serving works out to roughly 34g — this is the number most keto and low-carb tracking apps use. If you're managing type 2 diabetes, pre-diabetes or reactive hypoglycemia, use total carbs for insulin dosing calculations and treat net carbs as a rough guide for meal planning.
Ways to eat Domino's Pepperoni Pizza Slice (large)
- Treat domino's pepperoni pizza slice (large) as your main carb source for the meal — skip additional bread, rice or pasta on the side.
- Split a full serving of domino's pepperoni pizza slice (large) into two smaller portions to keep post-meal glucose steadier.
- Pair domino's pepperoni pizza slice (large) with 20–30g of protein and some healthy fat to flatten the blood-sugar response.
Frequently asked questions
Is Domino's Pepperoni Pizza Slice (large) keto-friendly?
Not really. 34g net carbs per 1 slice (110g) exceeds a full-day keto allowance for most people. It's a much better fit for a low-carb (100–150g/day) or balanced plan.
How many carbs in Domino's Pepperoni Pizza Slice (large) per 100 grams?
About 32.7g of carbs, 2.7g sugar and 291 calories per 100g of Domino's Pepperoni Pizza Slice (large).
How does Domino's Pepperoni Pizza Slice (large) affect blood sugar?
Moderate glycemic impact expected. If you're monitoring blood sugar, keep an eye on total portion size and combine with protein or fat.
Is Domino's Pepperoni Pizza Slice (large) good for weight loss?
A serving delivers 320 calories with 13g protein and 2g fiber. Foods that are relatively high in protein and fiber per calorie tend to be more filling — with a 5% combined protein-plus-fiber-to-calorie ratio, Domino's Pepperoni Pizza Slice (large) is best paired with a lean protein or vegetables so the meal keeps you full for longer.
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Open scannerSources & how these numbers are calculated
Nutrition values are consensus averages compiled from the USDA FoodData Central database for a typical 1 slice (110g) serving of Domino's Pepperoni Pizza Slice (large). Actual values vary with brand, variety, ripeness and preparation — always check the label on packaged products. Daily-value percentages reference the U.S. FDA 2,000-calorie adult reference (275g carbs, 50g added sugar, 50g protein, 78g fat, 28g fiber).
Content reviewed by Carb Lens editorial. Read our editorial policy for how we source, review and update food data.